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Research

Protein S Deficient Plasma Lyophilized, human citrated plasma, deficient for PS, for any protocol or research study where a source of human PS deficient plasma is required.

REAGENT CALIBRATOR CONTROL Product Name RS Ref. Presentation Product Name Ref. Product Name Ref. Protein S

Deficient Plasma

RUO DP110K 6 x 1 mL - - - -

FACTOR V LEIDEN (1)

Factor V Leiden (FV-L) mutation is the most common hereditary thrombophilia risk factor. Patients carrying FV-L mutation have an increased risk of venous thrombosis.

This genetic anomaly can be evidenced with clotting assays, performed in presence or absence of APC.

HEMOCLOT™ Quanti. VL Quantitative determination of FV-L, by measuring its resistance to the inactivation by APC, in the presence of PS, in human citrated plasma.

REAGENT CALIBRATOR CONTROLS Product Name RS Ref. Presentation Product Name Ref. Product Name Ref.

HEMOCLOT™ Quanti. VL

CE-IVD 510(k) CK065K

R1: 3 x 2 mL BIOPHEN™ V-L Plasma Calibrator

222401 BIOPHEN™ Normal

Control Plasma BIOPHEN™ V-L

Control Plasma

223201

223405R2: 3 x 1 mL

PROTEIN Z (PZ)

Research

ZYMUTEST™ Protein Z Measurement of human PZ in plasma, or in any fluid, by Elisa.

COMPLETE SOLUTION Product Name RS Ref. Presentation

ZYMUTEST™ Protein Z RUO RK031A 96 tests

PROTEIN S (PS) (1)

Congenital or acquired PS deficiencies are associated with an increased risk of venous thromboembolism.

In the early stages of inflammatory diseases, free PS concentration is decreased because of an elevation of C4b-BP. PS may be decreased in various contexts such as dicoumarol or L-asparaginase therapy, in hepatic disorders, nephrotic syndrome, during pregnancy, related to oral contraceptives intake or œstrogen therapy, viral infections, DIC. Free PS may also be decreased in new-borns. PS is slightly lower in females than in males.

Inherited PS deficiencies are classified into three types: Type I: decreased total and free PS levels (quantitative defects). Type II: decreased PS activity but normal antigenic levels (rare qualitative defects). Type III: normal levels of total PS but decreased free PS (free form distribution defect).

LIAPHEN™ Free Protein S Determination of free PS Antigen (free PS:Ag) in human citrated plasma with a latex turbidimetric assay.

REAGENT CALIBRATOR CONTROLS Product Name RS Ref. Presentation Product Name Ref. Product Name Ref. LIAPHEN™

Free Protein S Liquid and Ready to use

CE-IVD 120004 R1: 4 x 3 mL BIOPHEN™

Plasma Calibrator

222101

BIOPHEN™ Normal Control Plasma

BIOPHEN™ Abnormal Control Plasma

223201

223301 R2: 4 x 4.4 mL

HEMOCLOT™ Protein S Determination of PS activity in citrated human plasma with a clotting method.

REAGENT CALIBRATOR CONTROLS Product Name RS Ref. Presentation Product Name Ref. Product Name Ref.

HEMOCLOT™ Protein S CE-IVD

CK041K R1: 3 x 1 mL

BIOPHEN™ Plasma Calibrator

222101

BIOPHEN™ Normal Control Plasma

BIOPHEN™ Abnormal Control Plasma

223201

223301 R2: 3 x 1 mL

CK042K R1: 3 x 2 mL

R2: 3 x 2 mL

ZYMUTEST™ Free Protein S (II) Determination of Free PS (the activated Protein C (aPC) cofactor) in human plasma by Elisa.

COMPLETE SOLUTION Product Name RS Ref. Presentation ZYMUTEST™

Free Protein S (II)

CE-IVD RK015B on- demand

96 tests

ZYMUTEST™ Total Protein S Measurement of human Total PS in plasma, or in any fluid where Total PS can be present, by Elisa.

COMPLETE SOLUTION Product Name RS Ref. Presentation ZYMUTEST™

Total Protein S CE-IVD RK021A 96 tests

(1) cf Dedicated intructions for use (1) cf Dedicated intructions for use

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