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37
ANTITHROMBIN (AT) (1)
Spontaneous thromboembolic diseases are observed in presence of congenital or acquired deficiencies of antithrombin. These deficiencies are classified in 4 different groups: Type I: Decreased AT concentration and decreased AT activity; this is the most frequent case. Type II RS (Reactive Site): Normal AT concentration and decreased biological activity; a protein
abnormality is present at the active site. Type II HBS (Heparin Binding Site): Normal AT concentration, normal AT activity in the absence
of heparin, but decreased in its presence. Type II (Pleiotropic): Decreased AT concentration and activity; nonfunctional protein and at
a lowered level.
BIOPHEN™ AT anti - (h) - Xa LRT Determination of AT activity in human citrated plasma, using an anti-Xa chromogenic method (Human Xa).
REAGENT CALIBRATOR CONTROLS
Product Name RS Ref. Presentation Product Name Ref. Product Name Ref.
BIOPHEN™ AT anti-(h)- Xa LRT Liquid and Ready to use
CE-IVD 221123
R1: 3 x 3 mL BIOPHEN™
Plasma Calibrator
222101
BIOPHEN™ Normal Control Plasma
BIOPHEN™ Abnormal Control Plasma
223201
223301 R2: 3 x 3 mL
221127 R1: 4 x 7.5 mL R2: 4 x 7.5 mL
BIOPHEN™ AT LRT Determination of the heparin cofactor activity of AT in human citrated plasma, using an anti-Xa chromogenic method (Bovine Xa).
REAGENT CALIBRATOR CONTROLS Product Name RS Ref. Presentation Product Name Ref. Product Name Ref.
BIOPHEN™ AT LRT Liquid and Ready to use
CE-IVD 221111 R1: 4 x 11 mL BIOPHEN™
Plasma Calibrator
222101
BIOPHEN™ Normal Control Plasma
BIOPHEN™ Abnormal Control Plasma
223201
223301 R2: 4 x 4 mL
BIOPHEN™ Antithrombin Determination of AT activity in human citrated plasma, using an anti-Xa chromogenic method (Human Xa).
REAGENT CALIBRATOR CONTROLS Product Name RS Ref. Presentation Product Name Ref. Product Name Ref.
BIOPHEN™ Antithrombin
CE-IVD 510(k)
221102 R1: 2 x 2.5 mL
BIOPHEN™ Plasma Calibrator
222101
BIOPHEN™ Normal Control Plasma
BIOPHEN™ Abnormal Control Plasma
223201
223301
R2: 2 x 2.5 mL R3: 2 x 5 mL
221105
R1: 4 x 5 mL R2: 4 x 5 mL
R3: 4 x 10 mL
(1) cf Dedicated intructions for use