Thrombin Time (TT)*

TT is a screening test to assess abnormalities of fibrinogen and to detect thrombin inhibitors. It can be useful for the exploration of Disseminated Intravascular Coagulation (DIC) and liver diseases.
A prolonged TT can result from the presence of antithrombin activity induced by therapy (e.g. Heparin, Bivalirudin, Argatroban, Dabigatran), the presence of high concentrations of Fibrin/Fibrinogen degradation products or qualitative (dysfibrinogenemia) or quantitative abnormalities of Fibrinogen (deficiency, DIC, fibrinolysis, hepatic disorders including cirrhosis).
TT is normal in presence of a Factor XIII deficiency.

 

* cf Dedicated instructions for use